Takeda Pharmaceutical President of OBU Sells $973K in ADSs

Executive Summary

On November 4, 2026, Teresa Marie Bitetti, President of the Oncology Business Unit at Takeda Pharmaceutical Co Ltd ($TAK), filed a Form 4 reporting an open-market sale of 46,609 American Depositary Shares (ADSs) executed on November 2, 2026. The transaction totaled approximately $973,662 at an average price of $20.89 per share.

Transaction Details

• Date: November 2, 2026
• Transaction Code: S (Open-market sale)
• Volume: 46,609 ADSs
• Price: $20.89
• Proceeds: $973,662.01
• Rule 10b5-1 Plan: Not indicated (box unchecked)
• Post-Transaction Holdings: 214,501 ADSs (directly held)
• Footnotes: Holdings include 9,100 ADSs received from the vesting of dividend equivalent units not previously reported.

Ownership Impact & Significance

Prior to the sale, Bitetti held 261,110 ADSs. This transaction represents a disposition of approximately 17.8% of her direct equity stake, leaving her with 214,501 ADSs. Given the executive role and near-$1 million disposition size outside of an indicated Rule 10b5-1 trading arrangement, this transaction holds medium market significance.