FMR LLC Reports 10.7% Beneficial Ownership in Illumina Inc

Overview & Ownership Summary

On October 7, 2026, FMR LLC (jointly filing with Abigail P. Johnson) filed an initial/updated Schedule 13G pursuant to Rule 13d-1(b), disclosing a beneficial ownership stake of 10.7% in Illumina, Inc. ($ILMN) as of September 30, 2026.

Key Holding Details

• Issuer: Illumina, Inc. (CIK: 0001110803)
• Class of Security: Common Stock (CUSIP: 452327109)
• Aggregate Number of Shares Beneficially Owned: 16,169,439.04
• Percent of Class: 10.7%
• Voting & Dispositive Disaggregation:
  • Sole Voting Power: 15,355,486.88 shares
  • Shared Voting Power: 0.00 shares
  • Sole Dispositive Power: 16,169,439.04 shares
  • Shared Dispositive Power: 0.00 shares

Reporting Entity Context & Subsidiaries

FMR LLC filed as a parent holding company. Under Exhibit 99, subsidiaries that beneficially own shares of the class include:

• FIAM LLC
• Fidelity Diversifying Solutions LLC
• Fidelity Institutional Asset Management Trust Company
• Fidelity Management & Research Company LLC (beneficially owns 5% or greater of the class)
• Fidelity Management Trust Company
• Strategic Advisers LLC

Abigail P. Johnson is a Director, Chairman, and CEO of FMR LLC. The Johnson family group owns 49% of the voting power of Series B voting common shares of FMR LLC and may be deemed to form a controlling group under the Investment Company Act of 1940.

Market Impact & Significance

• Passive Nature: The filing is made under Rule 13d-1(b), including standard certification that the shares were acquired in the ordinary course of business without the intent to change or influence control of the issuer.
• Significance: A double-digit institutional ownership position (10.7%) signifies substantial institutional sponsorship by Fidelity/FMR LLC, reinforcing its role as one of the major blockholders of Illumina's equity.